Sickle Cell Disease is one that affects the blood cells. Ideally, everyone’s blood cells circular in shape but people with Sickle Cell have a number of blood cells that are shaped like a half letter C. That’s why its called “Sickle” Cell Disease because the cells are literally shaped like a sickle.
1. It is a genetical disease
Everyone of has a DNA. The DNA coding of an average human is GAG, CTC. For the RNA it is GAG. A person who has Sickle Cell Disease has those genes mutated. It shows as GTG, CAC for DNA and GUG for the RNA.
Children can easily inherit it from their parents if both parents have the sickle cell “trait”. If one parent has the disease or trait and the other one doesn’t, the child most likely won’t get the disease they will only inherit the trait of it.
2. Other regions besides Africa carry it
Although, we have more Africans living with sickle cell disease according to world statistics. But people from other regions such as India, South America, Central America, Saudi Arabia, and in the Caribbeans also carry it as well. You would hear more about it in African Americans because that is the most concentrated area that it is in.
3. There are four types of sickle cell disease
Not many people know that there are actually different versions of the sickle cell disease. The first one is called Hemoglobin SS. This one is considered the worst type and the symptoms are at the highest. This comes from the hemoglobin S gene from both parents.
The second one down is the hemoglobin SC. This one comes from one parent having the hemoglobin C gene and the other one having the S gene. The symptoms of this type are similar but a little less than SS.
The third one down is SB+ thalassemia. This one is caused by the Hb S gene causing red blood cells to appear smaller because of the beta protein not being produced.
Hemoglobin SB 0 thalassemia is the last type of sickle cell. This one is occasionally more severe compared to the Hb SS.Do you want to be the first to get these news,updates and vital info?